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KMID : 1103720220830051059
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Journal of the Korean Society of Radiology
2022 Volume.83 No. 5 p.1059 ~ p.1070
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Comparison of Computed Diffusion-Weighted Imaging b2000 and Acquired Diffusion-Weighted Imaging b2000 for Detection of Prostate Cancer
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Kim Yeon-Jeong
Kim Seung-Ho
Baek Tae-Wook
Park Hyung-In
Lim Yun-Jeong
Jung Hyung-Kyung
Kim Joo-Yeon
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Abstract
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Purpose : To compare the sensitivity of tumor detection and inter-observer agreement between acquired diffusion-weighted imaging (aDWI) b2000 and computed DWI (cDWI) b2000 in patients with prostate cancer (PCa).
Materials and Methods : Eighty-eight patients diagnosed with PCa by radical prostatectomy and having undergone pre-operative 3 Tesla-MRI, including DWI (b, 0, 100, 1000, 2000 s/mm2), were included in the study. cDWI b2000 was obtained from aDWI b0, b100, and b1000. Two independent reviewers performed a review of the aDWI b2000 and cDWI b2000 images in random order at 4-week intervals. A region of interest was drawn for the largest tumor on each dataset, and a Prostate Imaging-Reporting and Data System (PI-RADS) score based on PI-RADS v2.1 was recorded. Histologic topographic maps served as the reference standard.
Results : The study population’s Gleason scores were 6 (n = 16), 7 (n = 53), 8 (n = 9), and 9 (n = 10). According to the reviewers, the sensitivities of cDWI b2000 and aDWI b2000 showed no significant differences (for reviewer 1, both 94% [83/88]; for reviewer 2, both 90% [79/88]; p = 1.000, respectively). The kappa values of cDWI b2000 and aDWI b2000 for the PI-RADS score were 0.422 (95% confidence interval [CI], 0.240?0.603) and 0.495 (95% CI, 0.308?0.683), respectively.
Conclusion : cDWI b2000 showed comparable sensitivity with aDWI b2000, in addition to sustained moderate inter-observer agreement, in the detection of PCa.
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KEYWORD
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Magnetic Resonance Imaging, Diffusion, Neoplasm Grading, Prostate Cancer, Gleason Score
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